Putting Aging & Disease into Reverse

The Feel Good Diet Plan

There are four proven diets that can reverse disease and aging (oxidative stress).

  1. Low Glycotoxin Diet (Heat processing of foods causes Glycotoxins)
  2. Low AGE Diet (Advanced Glycation End Products)
  3. Alkaline Diet
  4. Low Oxysterols diet

It is easy to follow a diet that is a combination of all four of the above.

The types of diseases that can be reversed or improved by the above diets are:

  • Alzheimers
  • Atherosclerosis
  • Cancer
  • Osteoarthritis
  • Lung Emphysema
  • CVD
  • CKD
  • ND – Neurodegenerative Disease
  • MD – Macular Disease
  • COPD

Disease is a loss of homeostasis due to chronic oxidative stress.

Low Glycotoxin Diet

Cooked diets rich in absorbable glycotoxins have been shown to promote oxidative stress, cause renal damage, atherosclerosis, metabolic syndrome, fatty liver disease, cognitive dysfunction, delay wound healing and shorten lifespan.

Plant-based raw food diets are exceptionally low in glycotoxins and are recommended for cancer control. Raw food diets come with living enzymes and slow the growth of some cancers by down-regulating systemic levels of free IGF-I and promoting good insulin sensitivity. Uribarri measured the glycotoxin content of a wide range of common foods, prepared in various ways, and have summarized their findings in a monograph. By and large, low-fat plant-derived foods are the lowest in glycotoxins. The highest glycotoxin content is foods high in fat and protein – meat, poultry, fish, cheese, nuts, nut butters and tofu – which have been subjected to high heat during preparation. You can reduce the glycotoxin content of cooked food by cooking using lower-temperature cooking methods (slow cooker).


Low AGE Diet

A study published in the October/November issue of the Journal of Clinical Endocrinology and Metabolism, proved that a low AGE diet could result in weight loss and reverse several epidemic diseases, including diabetes, heart disease and kidney disease.

This proved to be effective in all study participants, including healthy persons and persons who had a chronic condition such as kidney disease,” said the study’s lead author Helen Vlassara, MD, Professor and Director of the Division of Experimental Diabetes and Aging at Mount Sinai School of Medicine.

“This suggests that oxidants may play a more active role than genetics in overwhelming our body’s defenses, which we need to fight off disease. It has been said that nature holds the power, but the environment pulls the trigger. The good news is that unlike genetics, we can control oxidant levels, which may not be an accompaniment to disease and aging, but instead due to the cumulative toxic influence of AGEs,” said Dr. Vlassara.

AGEs are harmful substances that are abundant in Western diets, and proliferate when foods are heated, pasteurized, dried, smoked, fried or grilled. Once absorbed in the body, AGEs adhere to tissues and oxidize them, causing inflammation which in turn can lead to disease. Numerous animal studies conducted by Dr. Vlassara and her team have shown that oxidative stress from high oxidant levels and inflammation related to long-term exposure to AGEs may increase the risk of diabetes, heart disease, kidney disease and other chronic conditions.

For the study, a subset of 40 healthy participants who were either between the ages or 18 and 45 or older than 60, and another nine patients with kidney disease, were randomly assigned to one of two diets. One group followed their own regular Western diet that was rich in AGEs. The second group followed a diet of similar caloric and nutrient content, but with only one-half the amount of AGEs, known as the “AGE-less diet.” Participants in the AGE-less intervention were advised to avoid grilling, frying or baking their food and instead were instructed to poach, stew, or steam their meals. There was no change in calories or nutrient intake during this period.

After four months on the AGE-less diet, blood AGE levels, lipid peroxides, inflammatory markers, and biomarkers of vascular function declined by as much as 60 percent in healthy participants. A reduction of similar magnitude was found in kidney patients after only one month on the AGE-less diet.

Researchers also found a positive effect on a cellular receptor for AGEs called AGER1, which is critical for the clearance of toxic AGEs from the body. The number of copies of the AGER1 gene was measured in circulating blood cells. Since this number was severely suppressed in participants with kidney disease, all of whom had very high levels of AGEs, the researchers speculate that important defense mechanisms can become “exhausted” as a result of chronically elevated AGEs. However, after a short period on the AGE-reduced diet, the number of AGER1 gene copies was restored to normal levels among patients with kidney disease.

The investigators believe that daily AGE consumption in the standard Western diet is at least three times higher than the safety limit for these oxidants. This could, in part, explain the changes seen in disease demographics.

Dr. Vlassara cautioned, “Even though the AGEs pose a more immediate health threat to older adults, they are a similar danger for younger people, including pregnant women and children, and this needs to be addressed. AGEs are ubiquitous and addictive, since they provide flavor to foods. But they can be controlled through simple methods of cooking, such as keeping the heat down and the water content up in food and by avoiding pre-packaged and fast foods when possible. Doing so reduces AGE levels in the blood and helps the body restore its own defenses.”

Journal Reference:

  1. Vlassara et al. Protection against Loss of Innate Defenses in Adulthood by Low Advanced Glycation End Products (AGE) Intake: Role of the Antiinflammatory AGE Receptor-1. Journal of Clinical Endocrinology & Metabolism, 2009; DOI: 10.1210/jc.2009-0089

Alkaline Diet

According to the acid-ash hypothesis, acidic ash makes you vulnerable to illness and disease, whereas alkaline ash is considered protective.

By choosing more alkaline foods, you should be able to “alkalize” your body and improve your health.

Food components that leave acidic ash include protein, phosphate, and sulfur, while alkaline components include calcium, magnesium, and potassium.

Certain food groups are considered acidic, alkaline, or neutral:

  • Acidic: meat, poultry, fish, dairy, eggs, grains, alcohol
  • Neutral: natural fats, starches, and sugars
  • Alkaline: fruits, nuts, legumes, and vegetables

Low Oxysterol Diet

Cholesterol, both HDL and LDL are needed by the body and are useful at any level. It is not a bad thing to have high cholesterol.

What is bad is oxidized cholesterol, this causes many health problems including atherosclerosis.

Another term for oxidized cholesterol is Oxysterol. Oxysterols are formed in the body from eggs or egg derived  products, fried food using vegetable or animal fats and pasteurized dairy products. You can reverse oxysterols in the body by eating foods high in antioxidants like blueberries or you can reduce eating foods high in oxysterols.

Alkaline Diet

Acidosis, Diet and our Health

Gutbiome Health

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